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Animal studies documented significant brain concentrations after oral administration, with cognitive effects comparable to subcutaneous injection

As the lesion progresses to fibrotic plaques as a result of continued inflammation, macrophage chemoattractants stimulate infiltration and proliferation of smooth muscle cells (Figure 3)

C., Potvin, D., Moyle, G., Soulban, G., Loughrey, H., Marsolais, C., Turner, R., Grinspoon, S

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Japan SLC, Hamamatsu, Japan) were housed under controlled temperature (approximately 23C), humidity (approximately 55%), and light (12 h/12 h light/dark cycle) conditions, and fed a regular diet (CRF-1